Anti-microfilarial activity of methanolic extract of Vitex negundo and Aegle marmelos and their phytochemical analysis.
Identifieur interne : 006C23 ( Main/Exploration ); précédent : 006C22; suivant : 006C24Anti-microfilarial activity of methanolic extract of Vitex negundo and Aegle marmelos and their phytochemical analysis.
Auteurs : K N Sahare [Inde] ; V. Anandhraman ; V G Meshram ; S U Meshram ; M V R. Reddy ; P M Tumane ; K. GoswamiSource :
- Indian journal of experimental biology [ 0019-5189 ] ; 2008.
Descripteurs français
- KwdFr :
- MESH :
- pharmacologie : Extraits de plantes, Filaricides.
- traitement médicamenteux : Filariose lymphatique.
- Aegle, Animaux, Brugia malayi, Feuilles de plante, Humains, Microfilaria, Médecine ayurvédique, Phytothérapie, Racines de plante, Ricinus, Vitex.
English descriptors
- KwdEn :
- MESH :
- chemical , pharmacology : Filaricides, Plant Extracts.
- chemistry : Plant Leaves, Plant Roots.
- drug effects : Brugia malayi, Microfilariae.
- drug therapy : Elephantiasis, Filarial.
- Aegle, Animals, Humans, Medicine, Ayurvedic, Phytotherapy, Ricinus, Vitex.
Abstract
In the present study, methanolic extracts of roots of Vitex negundo L. and extracts of leaves of Vitex negundo L., Ricinus communis L. and Aegle marmelos Corr. were explored for possible antifilarial effect against Brugia malayi microfilariae. It was observed that among the herbal extracts, root extract of Vitex negundo L. and leaves extract of Aegle marmelos Corr. at 100 ng/ml concentration showed complete loss of motility of microfilariae after 48 hr of incubation. Thin layer chromatography of the extracts revealed the presence of alkaloids, saponin and flavonoids in the roots of Vitex negundo L. and coumarin in the leaves of Aegle marmelos Corr.
PubMed: 18335811
Affiliations:
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It was observed that among the herbal extracts, root extract of Vitex negundo L. and leaves extract of Aegle marmelos Corr. at 100 ng/ml concentration showed complete loss of motility of microfilariae after 48 hr of incubation. Thin layer chromatography of the extracts revealed the presence of alkaloids, saponin and flavonoids in the roots of Vitex negundo L. and coumarin in the leaves of Aegle marmelos Corr.</div></front></TEI><affiliations><list><country><li>Inde</li></country></list><tree><noCountry><name sortKey="Anandhraman, V" sort="Anandhraman, V" uniqKey="Anandhraman V" first="V" last="Anandhraman">V. Anandhraman</name><name sortKey="Goswami, K" sort="Goswami, K" uniqKey="Goswami K" first="K" last="Goswami">K. Goswami</name><name sortKey="Meshram, S U" sort="Meshram, S U" uniqKey="Meshram S" first="S U" last="Meshram">S U Meshram</name><name sortKey="Meshram, V G" sort="Meshram, V G" uniqKey="Meshram V" first="V G" last="Meshram">V G Meshram</name><name sortKey="Reddy, M V R" sort="Reddy, M V R" uniqKey="Reddy M" first="M V R" last="Reddy">M V R. Reddy</name><name sortKey="Tumane, P M" sort="Tumane, P M" uniqKey="Tumane P" first="P M" last="Tumane">P M Tumane</name></noCountry><country name="Inde"><noRegion><name sortKey="Sahare, K N" sort="Sahare, K N" uniqKey="Sahare K" first="K N" last="Sahare">K N Sahare</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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